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E., Dohna-Schwake, C., Hanssler, L., Neudorf, U., Hoyer, P

Gln enters tumor cells through the action of transporter proteins and is converted into glutamate via dehydrogenation, catalyzed by GLS

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Studies have demonstrated that Hinge binds to HGF with high affinity blocking its dimerization and acting as a potent inhibitor of HGF-dependent cellular activities including MDCK proliferation

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